Application of resina draconis to preparation of medicine for treating acute liver injury caused by hepatectomy

龙血竭在制备治疗肝切除急性肝损伤修复的药物中的应用

Abstract

本发明公开了龙血竭在制备治疗肝切除肝损伤修复的药物中的应用。将龙血竭经过二次85%乙醇提取纯化,减压回收,得流浸膏,将浓缩物喷雾干燥,过120目筛得龙血竭浸膏粉,将龙血竭浸膏粉用CMC‑Na混悬,或用1%‑50%甘油溶解,用0.2μm滤膜过滤,制成药物制剂,用于口服或注射,0.1‑5mg/kg体重,然后进行肝功能指标检测观察肝组织修复情况,发现肝功能恢复正常,龙血竭具有促进肝切除肝损伤修复的作用。
The invention discloses application of resina draconis to preparation of a medicine for treating acute liver injury caused by hepatectomy. According to the application, resina draconis is extracted and purified with 85% ethanol twice and reduced-pressure recovery is performed to obtain fluid extract, the concentrate is spray-dried and screened by a 120-mesh screen to obtain resina draconis extract powder, the resina draconis extract powder is suspended in CMC-Na or dissolved with 1%-50% glycerol, filtering is performed by a 0.2mu m filter membrane to obtain a medicine preparation, the medicine preparation is orally administered or injected at a dosage of 0.1-5mg/kg weight, liver function index detection is performed to observe the liver tissue repairing condition, and the results show that the liver function is restored to be normal, so that the resina draconis has the effect of promoting the repairing of liver injury caused by hepatectomy.

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